Purpose This study aimed to evaluate the effect of core stability exercises on energy expenditure during gait in subacute stroke patients. Methods The study included 24 subacute stroke patients randomly allocated to the experimental group (n=12) and control group (n=12). Patients in the experimental group performed the core stability exercises (20 min) and conventional physical treatment (20 min), while those in the control group performed conventional physical treatment (40 min) only. Both groups performed training five times a week for 4 weeks. Outcome assessments evaluated energy cost, physiological cost index, and walking speeds. The patients were assessed before and after intervention. The ShapiroWilk test was used to assess normalization. Withingroup differences were analyzed using the paired t test, while betweengroup differences were analyzed using an independent t test. Results After 4 weeks of exercise, both the groups showed significant increased walking speed and significant decreased energy cost, physiological cost index (p<.05). However, the experimental group was more effective than control group was increasing in walking speed (p<.05) and decreasing in energy cost (EC), physiological cost index (PCI) (p<.05). Conclustion We suggest that core stability exercises effectively improve walking speed and energy efficiency during gait in subacute stroke patients.