pISSN : 3058-6941 eISSN: 3058-695X
Open Access, Peer-reviewed
pISSN : 3058-6941 eISSN: 3058-695X
Open Access, Peer-reviewed
Kyoung-Bo Lee,Sang-Ho Lee,Seong-Hoon Lim
https://dx.doi.org/10.17817/2020.02.11.111503 Epub 7th March, 2020
Abstract
Purpose Agenesis of the corpus callosum (AgCC) is one of several disorders of the structure that connects the two hemispheres of the brain. We describe two patients with AgCC and compare their magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) findings with those of healthy controls. Methods Two females with AgCC underwent brain MRI. DTIStudio software (CMRM, Johns Hopkins Medical Institute, MD, USA) was used to reconstruct the corpus callosum (CC) fibers. Results MRI revealed periventricular plaques, complete CC agenesis of corpus callosum, and a residual anterior commissure (AC). In the DTI images of normal subjects, transcallosal fiber tracts were apparent, and formed many more connections to the frontal area than was the case in the patients. Conclusion Early diagnosis and intervention may improve the social and developmental outcomes of patients with AgCC. Symptoms and seizures must be managed. A focus on right/left co-ordination render the condition much more manageable than is otherwise the case.
Keywords
Agenesis of the corpus callosum Clinical findings MRI Diffusion tensor imaging
