Purpose The aim of this study was to determine the effects of facilitating reciprocal inhibition of ankle dorsi-Plantar flexors on leg muscle activation patterns during the sit to stand movement. Methods Fifteen patients with hemiplegia were randomly recruited from Y hospital. Subjects stood up from an armless plinth with a comfortable and self-paced speed. Onset-offset times of leg muscles during the sit to stand movement were measured using surface electromyograph and a force platform. Results The mean onset time of muscle activation in paretic tibialis anterior (TA) was significantly earlier after treatment (p<.05), and soleus (SOL), which showed a significant delay (p<.05) in paretic side. However, there was no significant difference between pre- and post-treatment in rectus femoris (RF) and biceps femoris (BF) (p>.05) in paretic side. There were significant differences between pre- and post-treatment in onset time of both paretic and non-paretic leg muscle (p<.05). The recruitment order of muscle activity in pre-treatment was in sequence of RF, SOL, then followed by TA activation. In post-treatment, it was in order of RF activation, TA, BF and then SOL activation. Conclusion It was found that the therapeutic exercise to facilitate the intrinsic muscle and antagonistic activity of SOL in paretic foot and leg made significant effects on enhancing reciprocal inhibition for efficient postural control.