Purpose The aim of this study was to determine the effect of Whole-Body Vibration on gross motor function and balance, gait of children with cerebral palsy. Methods The Design is ABA design of single-subject experimental design. This study participate 2 subjects for 7 years old who were diagnosed children with spastic cerebral palsy. Baseline(A) and Baseline(A’) phases were received not WBV, Intervention(B) phase provided with 30 minutes WBV in 10 session. All subjects were measured with the Gross Motor Function Measure(GMFM-66), Pediatric Balance Scale(PBS), One leg standing, Gait analysis in session and at follow-up. Results The results showed that the subjects increased GMFM-66 score and remained in the assessment after the intervention. But the subject 2 was decrease again after baseline(A’). PBS of both subjects increased until after intervention but decreased during baseline(A’). In the one leg standing, both subjects increased after the baseline(A). Especially, the sessions exceeding the two standard deviation in the intervention process were 5 times and 8 times, respectively. The gait symmetry index of both subjects increased after intervention. Conclusion WBV was effective in improving gross motor and balance, gait in children with cerebral palsy.