Purpose This study investigated the correlation among the manual function test (MFT), Korean version of the modified Barthel index (KMBI), twopoint discrimination (TPD), and stereognosis (ST) through tactile feedback training of the hands and upper limbs. Methods Patients with motor impairment were recruited and divided into two groups as part of a longitudinal study of effects on hand function and activities of daily living during twopoint discrimination and stereognosis recovery. Inclusion criteria were unilateral neglect, combined sensory deficits and motor weakness. Patients participated in 4 weeks of physical therapy and occupational therapy involving tactile feedback training for the upper limbs using sensory information. Results In the unilateral neglect group, functioning statistically improved for TPD, ST, MFT, and KMBI. In the sensorimotor deficit group, functioning statistically improved for MFT, and KMBI. TPD and MFT results significantly improved between the groups. The relationship between MFT, ST, and TPD was negative. Conclusion tactile feedback training for stroke patients with accompanying unilateral neglect or somatosensory impairment may be used clinically as an important way to promote upper limb function and performance of activities of daily living. In addition, stereognosis and twopoint discrimination may be used as important sensory indices for functional task performance.