Purpose This study sought to investigate the effects of lower-extremity robotic therapy combined with 5 Hz high-frequency repetitive transcranial magnetic stimulation on the Berg Balance Scale (BBS), Timed Up & Go Test (TUG) and 10 m walk in stroke patients. Methods A total of 14 stroke patients participated in the study—namely, seven persons in the lower-extremity robotic therapy group who used 5 Hz high-frequency repetitive transcranial magnetic stimulation on the cerebral hemisphere on the damaged side (5Hz-rTMSRG) and seven persons in the general robotic walking therapy group (GRG). The subjects’ training period was 30 min/day, 3 days/week, for 4 weeks, and both groups performed functional evaluations related to balance and walking before and after the intervention. Results A comparison of the results obtained by the two groups revealed that those in the 5Hz-rTMSRG showed significant differences in the BBS, TUG, and 10 m walk results after the intervention (p<0.05). In addition GRG showed significant differences in the BBS, TUG, and 10 m walk results (p<0.05). When comparing the balance and gait evaluations after the intervention between the two groups, significant differences were found in the 5Hz-rTMSRG and GRG in terms of the BBS, TUG,

and 10 m walk results (p<0.05 and p<0.001, respectively). Conclusion These results revealed that lowerlimb robotic

therapy combined with 5 Hz highfrequency repetitive transcranial magnetic stimulation had a more positive effect on the

BBS and TUG results of stroke patients than general lowerlimb robotic therapy.